• Blood biomarkers and Type 2 Diabetes Mellitus - Repeated measurements of blood biomarkers in Type 2 Diabetes Mellitus cases and controls; longitudinal assessments and associations 

      Allaoui, Giovanni (Doctoral thesis; Doktorgradsavhandling, 2023-11-24)
      Type 2 diabetes (T2DM) is a chronic metabolic disease and is characterised by insulin resistance and insufficient insulin secretion, resulting in hyperglycaemia. The prevalence of diabetes was estimated to be 10.5% in 2021, globally. T2DM is associated with several complications, including cardiovascular complications, degradation of nerve fibres and eyesight, and impaired kidney function, especially ...
    • Gradually decreasing daylength after smoltification induced by “winter signal“ reduced sexual maturation in male Atlantic salmon 

      Skjold, Vetle; Rørvik, Kjell-Arne; Sveen, Lene; Burgerhout, Erik; Mota, Vasco C.; Weihe, Runi; Ytrestøyl, Trine; Bou, Marta; Jacobsen, Hans Jakup; Allaoui, Giovanni; Fuskevåg, Ole-Martin; Dessen, Jens-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-16)
      Introduction: Maturation in seawater-adapted (smoltified) male Atlantic salmon is undesirable yet frequently reported in fish weighing up to 1 kg reared under intensive conditions in land-based facilities. Although the photoperiod regulates both smoltification and maturation, the optimal post-smoltification regimen for the prevention of maturation is unclear.<p> <p>Methods: In this study, ...
    • Longitudinal changes in blood biomarkers and their ability to predict type 2 diabetes mellitus—The Tromsø study 

      Allaoui, Giovanni; Rylander, Charlotta; Averina, Maria; Wilsgaard, Tom; Fuskevåg, Ole Martin; Berg, Vivian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-11)
      Introduction: Identification of individuals at high risk of developing type 2 diabetes mellitus (T2DM) is important for early prevention of the disease. Once T2DM is established, it is difficult to treat and is associated with cardiovascular complications and increased mortality. We aimed to describe pre- and post-diagnostic changes in blood biomarker concentrations over 30 years in individuals ...
    • Longitudinal changes in vitamin D concentrations and the association with type 2 diabetes mellitus: the Tromsø Study 

      Allaoui, Giovanni; Rylander, Charlotta; Fuskevåg, Ole Martin; Averina, Maria; Wilsgaard, Tom; Brustad, Magritt; Jorde, Rolf; Berg, Vivian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-02)
      Aim We aimed to investigate the relationship between pre- and post-diagnostic 25-hydroxyvitamin D (25(OH)D) concentrations and type 2 diabetes (T2DM) over a period of 30 years in individuals who developed T2DM compared to healthy controls.<p> <p>Methods This case–control study included 254 participants with blood samples collected at fve diferent time-points (T1–T5) between 1986 and 2016. Of the ...